Cynara scolymus L. extract and betaine supplementation in sows during lactation
Keywords:animal nutrition, animal performance, sow feeding, piglets
Introduction. The modern sow has the genetic capacity to produce a greater number of piglets per litter and a higher milk production, which means that the animal has higher nutrient requirements. Objective. To evaluate the performance of sows and their progeny to the supplementation of a commercial product based on artichoke dry extract (Cynara scolymus) and betaine hydrochloride during the lactation period. Materials and methods. The study was carried out during the first semester of 2020, in the province of Limón, Costa Rica. A total of 42 lactating sows were used and distributed in three treatments: control diet (T1), control diet + 0.25 kg t-1 of commercial product (T2), and control diet + 0.50 kg t-1 of commercial product (T3); the diets were isoproteic and isocaloric. Results. The inclusion of the additive showed a tendency to improve (p=0.09) the parameters evaluated in the sow. Body condition score loss was lower (p=0.03) with the T2, while supplementation with 0.50 kg t-1 presented intermediate results. There were no significant differences (p>0.05) between treatments for the parameters evaluated in the litters (weaning weight, weight gain, and number of weaned piglets by sow). Conclusion. The use of the additive showed a tendency to improve feed intake in the sow during the lactation period, reducing body weight loss and corporal condition during this period. The inclusion of the additive did not improve the performance in the piglets. piglets/sow). Conclusion. The use of the additive tended to improve important parameters in the sow during the lactation period, however, more research is needed on the animal's response to the additive during lactation and in the following cycle to obtain conclusive results.
Abdo, Z. M. A., Radwan, N. L., & Selim, N. A. (2007). The effect of artichocke leaves meal on the utilization of dietary energy for broiler chicks. International Journal of Poultry Science, 6(12), 973–982. https://doi.org/10.3923/ijps.2007.973.982
Berchieri-Ronchi, C. B., Kim, S. W., Zhao, Y., Correa, C. R., Yeum, K. -J., & Ferreira, A. L. A. (2011). Oxidative stress status of highly prolific sows during gestation and lactation. Animal, 5(11), 1774–1779. https://doi.org/10.1017/S1751731111000772
Byrne, C. S., Chambers, E. S., Morrison, D. J., & Frost, G. (2015). The role of short chain fatty acids in appetite regulation and energy homeostasis. International Journal of Obesity, 39, 1331–1338. https://doi.org/10.1038/ijo.2015.84
Cabezón, F. A, Schinckel, A. P., Richert, B. T., Stewart, K. R., Gandarillas, M., Pasache, M., & Peralta, W. A. (2016). Effect of betaine supplementation during summer on sow lactation and subsequent farrowing performance. The Professional Animal Scientist, 32(5), 698–706. https://doi.org/10.15232/pas.2016-01532
Clowes, E. J., Aherne, F. X., Foxcroft, G. R., & Baracos, V. E. (2003). Selective protein loss in lactating sows is associated with reduced litter growth and ovarian function. Journal of Animal Science, 81(3), 753–764. https://doi.org/10.2527/2003.813753x
Costermans, N. G. J., Soede, N. M., Middelkoop, A., Laurenssen, B. F. A., Koopmanschap, R. E., Zak, L. J., Knol, E. F., Keijer, J., Teerds, K. J., & Kemp, B. (2020). Influence of the metabolic state during lactation on milk production in modern sows. Animal, 14(12), 2543–2553. https://doi.org/10.1017/S1751731120001536
De Bettio, S., Maiorka, A., Barrilli, L. N. E., Bergsma, R., & Silva, B. A. N. (2015). Impact of feed restriction on the performance of highly prolific lactating sows and its effect on the subsequent lactation. Animal, 10(3), 396–402. https://doi.org/10.1017/S1751731115002001
Dirección de Alimentos para Animales. (2022). Consulta oficial de establecimientos. Servicio Nacional de Salud Animal. https://sis.senasa.go.cr/daasire/Empresa/Empresa_publica?filtar=igusol
Eissen, J. J., Apeldoorn, E. J., Kanis, E., Verstegen, M. W. A., & de Greef, K. H. (2003). The importance of a high feed intake during lactation of primiparous sows nursing large litters. Journal of Animal Science, 81(3), 594–603. https://doi.org/10.2527/2003.813594x
Eissen, J. J., Kanis, E., & Kemp, B. (2000). Sow factors affecting voluntary feed intake during lactation. Livestock Production Science, 64(2–3), 147–165. https://doi.org/10.1016/S0301-6226(99)00153-0
Eklund, M., Bauer, E., Wamatu, J., & Mosenthin, R. (2005). Potential nutritional and physiological functions of betaine in livestock. Nutrition Research Reviews, 18(1), 31–48. https://doi.org/10.1079/nrr200493
Fu, R., Wang, Q., Kong, C., Liu, K., Si, H., & Sui, S. (2021). Mechanism of action and the uses betaine in pig production. Journal of Animal Physiology and Animal Nutrition, 106(3), 528–536. https://doi.org/10.1111/jpn.13633
Gessner, D. K., Gröne, B., Rosenbaum, S., Most, E., Hillen, S., Becker, S., Erhardt, G., Reiner, G., Ringseis, R., & Eder, K. (2015). Effect of a negative energy balance induced by feed restriction on pro-inflammatory and endoplasmic reticulum stress signalling pathways in the liver and skeletal muscle of lactating sows. Archives of Animal Nutrition, 69(5), 411–423. https://doi.org/10.1080/1745039X.2015.1075670
Hawe, S. J., Scollan, N., Gordon, A., & Magowan, E. (2020). Impact of sow lactation feed intake on the growth and suckling behavior of low and average birthweight pigs to 10 weeks of age. Translational Animal Science, 4(2), 655–665. https://doi.org/10.1093/TAS/TXAA057
Kempson, S. A., Vovor-Dassu, K., & Day, C. (2013). Betaine transport in kidney and liver: User of betaine in liver injury. Cellular Physiology and Biochemistry, 32(suppl, 1), 32–40. https://doi.org/10.1159/000356622
Kim, S. W., Weaver, A. C., Shen, Y. B., & Zhao, Y. (2013). Improving efficiency of sow productivity: nutrition and health. Journal of Animal Science and Biotechnology, 4, Article 26. https://doi.org/10.1186/2049-1891-4-26
Leroy, G., Grongnet, J. F., Mabeau, S., Le Corre, D., & Baty-Julien, Ć. (2010). Changes in inulin and soluble sugar concentration in artichokes (Cynara scolymus L.) during storage. Journal of the Science of Food and Agriculture, 90(7), 1203–1209. https://doi.org/10.1002/jsfa.3948
Martínez, G., Diéguez, S. N., Rodríguez, E., Decundo, J. M., Romanelli, A., Fernández Paggi, M. B., Pérez Gaudio, D. S., Amanto, F. A., & Soraci, A. L. (2018). Effect of Cynara scolymus and Silybum marianum extracts on bile production in pigs. Journal of Applied Animal Research, 46(1), 1059–1063. https://doi.org/10.1080/09712119.2018.1456441
Mendoza, S. M., Boyd, R. D., Remus, J., Wilcock, P., Martinez, G. E., & van Heugten, E. (2020). Sow performance in response to natural betaine fed during lactation and post-weaning during summer and non-summer months. Journal of Animal Science and Biotechnology, 11, Article 69. https://doi.org/10.1186/s40104-020-00471-0
Mohamed, S. H., Ahmed, H. H., Farrag, A. R. H., Abdel-Azim, N. S., & Shahat, A. A. (2013). Cynara scolymus for relieving on nonalcoholic steatohepatitis induced in rats. International Journal of Pharmacy and Pharmaceutical Sciences, 5(1), 57–66.
R Core Team. (2020). R: A language and environment for statistical computing. R Foundation for Statistical Computing. https://www.R-project.org/
Radzikowski, D., & Milczarek, A. (2021). Selected feed additives used in pig nutrition. Journal of Central European Agriculture, 22(1), 54–65. https://doi.org/10.5513/JCEA01/22.1.2927
Ramis, G., Evangelista, J. N. B., Quereda, J. J., Pallarés, F. J., De La Fuente, J. M., & Muñoz, A. (2011). Use of betaine in gilts and sows during lactation: Effects on milk quality, reproductive parameters, and piglet performance. Journal of Swine Health and Production, 19(4), 226–232. https://www.aasv.org/shap/issues/v19n4/v19n4p226.html
Salekzamani, S., Ebrahimi-Mameghani, M., & Rezazadeh, K. (2019). The antioxidant activity of artichoke (Cynara scolymus): A systematic review and meta-analysis of animal studies. Phytotherapy Research, 33(1), 55–71. https://doi.org/10.1002/ptr.6213
Salem, M. B., Affes, H., Ksouda, K., Dhouibi, R., Sahnoun, Z., Hammami, S., & Zeghal, K. M. (2015). Pharmacological Studies of Artichoke Leaf Extract and Their Health Benefits. Plant Foods for Human Nutrition, 70, 441–453. https://doi.org/10.1007/s11130-015-0503-8
Singh, A., & Chelikani, P. (2019). Peptide YY mediates the satiety effects of the short chain fatty acid-butyrate (P08-004-19). Current Developments in Nutrition, 3(Supplement 1), Article nzz044.P08-004-19. https://doi.org/10.1093/cdn/nzz044.P08-004-19
Sulabo, R. C., Jacela, J. Y., Tokach, M. D., Dritz, S. S., Goodband, R. D., DeRouchey, J. M., & Nelssen, J. L. (2010). Effects of lactation feed intake and creep feeding on sow and piglet performance. Journal of Animal Science, 88(9), 3145–3153. https://doi.org/10.2527/jas.2009-2131
Sureshkumar, S., Baek, D. H., & Kim, I. H. (2021). Influences of betaine supplementation on growth performance and fecal score in sows and their piglets fed a corn soybean meal- based diet. Korean Journal of Agricultural Science, 48(1), 1–9. https://doi.org/10.7744/kjoas.20200030
Wang, M., Simon, J. E., Aviles, I. F., He, K., Zheng, Q. -Y., & Tadmor, Y. (2003). Analysis of antioxidative phenolic compounds in artichoke (Cynara scolymus L.). Journal of Agricultural and Food Chemistry, 51(3), 601–608. https://doi.org/10.1021/jf020792b
Weather Sark. (2021). El clima y el tiempo promedio en todo el año en Siquirres Costa Rica. https://bit.ly/3CGvoN3
Weitkunat, K., Stuhlmann, C., Postel, A., Rumberger, S., Fankhänel, M., Woting, A., Petzke, K. J., Gohlke, S., Schulz, T. J., Blaut, M., Klaus, S., & Schumann, S. (2017). Short-chain fatty acids and inulin, but not guar gum, prevent diet-induced obesity and insulin resistance through differential mechanisms in mice. Scientific Reports, 7, Article 6109. https://doi.org/10.1038/s41598-017-06447-x
Williams, A. M., Safranski, T. J., Spiers, D. E., Eichen, P. A., Coate, E. A., & Lucy, M. C. (2013). Effects of a controlled heat stress during late gestation, lactation, and after weaning on thermoregulation, metabolism, and reproduction of primiparous sows. Journal of Animal Science, 91(6), 2700–2714. https://doi.org/10.2527/jas.2012-6055
Wood, S. N. (2017). Generalized additive models: An introduction with r (2nd ed.) Chapman, & Hall/CRC.
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