Supplementary Files
Keywords
Brugada; muerte súbta; fibrilación ventricular.
Abstract
Brugada Syndrome is an inherited condition whose diagnosis is based on a electrocardiographic pattern, which is associated with a risk of ventricular fibrillation and sudden death. The literature mentions that the causal mechanism may be related to an abnormal repolarization of the right ventricle related to sodium channel dysfunction. The latest evidence points to an important genetic role in up to a third of patients. The treatment is complex especially in asymptomatic patients, but the trend is the use of an implantable defibrillator. The following is an electrocardiographic case of Sindrome de Brugada, from which its characteristic pattern and clinical importance will be described.
References
Brugada J Campuzano O Arbelo E Sarquella-Brugada G Brugada R. Present status of Brugada Syndrome. JACC. 2018;9:1046-1059.
Probst V Wilde AA Barc J et al. SCN5A mutations and therole of genetic background in the pathophysiology of Brugada Syndrome. Circ Cardiovasc Genet 2009;2:552-557.
Brugada R Campuzano O Sarquella Brugada G et al. Brugada syndrome. Methodist Debakey Cardiovasc J. 2014;10(1):25–28.
Probst V Veltmann C Eckardt L et al. Long-term prog-nosis of patients diagnosed with Brugada syndrome: resultsfrom the FINGER Brugada Syndrome Registry. Circulation. 2010;121:635-643.
Arnalsteen-Dassonvalle E Hermida JS Kubala M et al. Ajma-line challenge for the diagnosis of Brugada syndrome: which protocol? Arch Cardiovasc Dis. 2010;103:570-578.
Batchvarov VN Govindan M Camm AJ Behr ER. Significance of QRS prolongation during diagnostic ajmaline testing patients with suspected Brugada syndrome. Heart Rhythm. 2009;6:625-631.
Nagase S Hiramatsu S Morita H et al. Electroanatomical correlation of repolarization abnormalities in Brugada syndrome: detection of type 1 electrocardiogram in the right ventricular outflow tract. J Am Coll Cardiol. 2010; 56:2143–2145.
Gourraud J Barc J Thollet A Marec H Probst V. Brugada syndrome: Diagnosis, risk stratification and management. Archive of Cardiovascular Disease. 2017; 110: 188-195.