Supernumerary premolars have received special attention due to their development during adolescence, representing a dental anomaly of number that could be attributed to a “third dentition” of human species. The goal of its treatment is to avoid possible interference in occlusal development, as long as the benefits of supernumerary removal outweigh its risks. This is a case report of the orthodontic and surgical management of a patient that has been in clinical and radiographic follow-up along eight years (since childhood through adolescence) with the emergence of non-syndromic multiple supernumerary premolars, showing an apparent familiar pattern.

Keywords: Adolescence; Maxillofacial Surgery; Orthodontics; Premolars; Supernumerary.